90-Second Read: Andes Hantavirus update

Outbreak linked to MV Hondius According to the World Health Organization (WHO), as of 8 May, a total of 8 cases, including 3 deaths (case fatality ratio 38%), have been reported. One case previously reported as suspected has now been reclassified as a non-case after testing negative for Andes (ANDV) virus through specific polymerase chain reaction (PCR) and serology. Podcast: Andes virus: Outbreak linked to a super-spreader event in Argentina A total of 149 persons embarked the ship at the beginning of the journey, including 88 passengers and 61 crew. The current hypothesis is that some passengers were exposed to ANDV while spending time in Argentina (where ANDV is endemic) before embarking the ship, and may subsequently have transmitted the virus to other passengers onboard.

They report they are also coordinating with international partners to align public health guidance and has already issued health guidance to affected Americans via the State Department. The risk to the public's health in the United States is considered extremely low at this time. In the Americas, Hantaviruses can cause Hantavirus pulmonary syndrome (HPS), a severe and potentially deadly disease that affects the lungs. Epidemiological investigations are underway to determine the source of exposure, including on the travel history and potential exposures of the first case.

As a precaution, CDC is working to increase awareness of the outbreak among travelers, public health agencies, laboratories, and healthcare professionals nationwide. Among patients who have severe respiratory symptoms, the case fatality rate has been estimated at approximately 38%. Although rare, spread between people has typically required close, prolonged contact with a symptomatic person. Symptoms of HPS caused by Andes virus usually appear within 4-42 days after exposure.

The ship had been on a cruise in the Southern Atlantic after departing from Argentina on 1 April and was en route to Cabo Verde. Right now, there are no symptomatic passengers on board. Disembarkation will take place using safe procedures, and health screening and infection control measures will be followed via a coordinated response prior to the repatriation of passengers to their countries of residence.